Scooter's Supplies for Chronic Renal Failure (CRF)

About IV Fluids - LRS and Multi-Electrolyte


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The fluids prescribed to "maintain" CRF cats are usually Lactated Ringer's Solution (LRS) and multi-electrolyte solutions such as Normosol-R (Hospira), Isolyte S (B.Braun), Plasma-Lyte A (Baxter).  All these solutions are "buffered," LRS with lactate and the multi-electrolye solution with acetate and gluconate.  These buffers help deal with the metabolic acidosis so common in CRF cats.  LRS is the usual maintenance prescription for CRF cats; the multi-electrolyte solutions are usually prescribed when calcium is high and vets are worried that the small amount of calcium supplemented by LRS (see table 1 below) may throw a cat into hypercalcemia (high calcium).

...

Table 1.  Comparison of LRS and Multi Electrolye Solutions
Electrolytes (mEq) per Liter

Trade Name

LRS

Plasma-Lyte A

Normosol-R

Isolyte S

Manufacturer

Many

Baxter

Hospira

B.Braun

Sodium

130

140

140

140

Potassium

4

5

5

5

Calcium

3

 

 

 

Magnesium

 

 3

3

3

Chloride

109

98

98

98

Lactate

28

 

 

 

Acetate

 

27

27

27

Gluconate

 

23

23

23

pH

6.5

7.4

6.6 or 7.4

6.7


Table 2.  Ingredients / Concentration - MGs per 100 mL
LRS and Multi Electrolyte Injectable Solutions

Ingredient

Lactated Ringer's
(Many)

Isolyte S
(B.Braun)

Normosol-R
(Hospira)

Plasma-Lyte A 
(Baxter)

Magnesium Chloride

-

30

30

30

Potassium Chloride

30

37

37

37

Sodium Acetate

-

370

222

368

Sodium Chloride

600

530

526

526

Sodium Gluconate

-

500

502

502

Sodium Lactate

300

-

-

-

Calcium Chloride

20

-

-

-

pH

6.5-6.6

6.7

6.6 or 7.4

7.4


 

 

This web site is a product of me, David Jacobson. The information presented here is not guaranteed.  Contact the vendors listed directly for their current prices and policies.  Feel free to link this page to other pages and web sites dealing with the medical treatment of cats and dogs.  And please contact me with any updated information or additional vendors, or your comments, criticisms and suggestions.  I appreciate your help.

 This web site first went online in April 2000.  It was dedicated to Scooter in September 2003.

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